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Suicide with depression

Disease name Suicide with depression
Classfication Nervous system disease
Related Enzyme(s)
EFO
DOID
OMIM
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NCI
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Definition

Gene symbol Species Enzyme Editing site(s) Editing Type PMID RADAR REDIportal Description
PDE8A Human ADAR1 5 NA Altered editing may contribute to the modulation of gene regulation and ultimately, immune functions in SLE and play an important role in the initiation and propagation of SLE pathogenesis;The observation of region-specific alterations of RNA editing of PDE8A in the cortex of suicide decedents with major depression raises the possibility of providing a marker for discriminating between suicides and control groups and suggests an immune response-related brain mechanism for suicide.